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Manikanta, K. and Naveen Kumar, S. K. and Hemshekhar, M. and Kemparaju, K. and Girish, K. S. (2020) ASK1 inhibition triggers platelet apoptosis via p38-MAPK-mediated mitochondrial dysfunction. Haematologica, 105 (8). E419-E423. ISSN 0390-6078
Paul, Manoj and Manikanta, K. and Hemshekhar, M. and Sundaram, Mahalingam S. and Naveen, S. and Ramesh, T. N. and Kemparaju, K. and Girish, K. S. (2020) Bisdemethoxycurcumin promotes apoptosis in human platelets via activation of ERK signaling pathway. Toxicology in Vitro, 63. ISSN 0887-2333
Naveen Kumar, S. K. and Hemshekhar, M. and Jagadish, Swamy and Manikanta, K. and Vishalakshi, G. J. and Kemparaju, K. and Girish, K. S. (2020) Melatonin restores neutrophil functions and prevents apoptosis amid dysfunctional glutathione redox system. Journal of Pineal Research, 69 (3). ISSN 1600-079X
Hemshekhar, M. and Thushara, Ram M. and Naveen Kumar, S. K. and Manoj Paul and Sundaram, M. S. and Kemparaju, K. and Girish, K. S. (2018) Bone degeneration, inflammation and secondary complications of arthritis: Potential targets and their natural inhibitors. Mini-Reviews in Medicinal Chemistry, 18 (3). pp. 244-275.
Vishalakshi, G. J. and NaveenKumar, S. K. and Hemshekhar, M. and Mahendra, M. and Kemparaju, K. and Girish, K. S. (2018) Para-tertiary butyl catechol (PTBC), an industrial antioxidant induces human platelet apoptosis. Environmental texicology. pp. 1-9.
Vishalakshi, G. J. and Hemshekhar, M. and Kemparaju, K. and Girish, K. S. (2018) Para-tertiary butyl catechol induces eryptosis in vitro via oxidative stress and hemoglobin leakage in human erythrocytes. Toxicology in Vitro, 52. 286 - 296. ISSN 1879-3177
Naveen Kumar, S. K. and Sharath Babu, B. N. and Hemshekhar, M. and Kemparaju, K. and Girish, K. S. and Mugesh, G. (2018) The role of reactive oxygen species and ferroptosis in heme-mediated activation of human platelets. ACS Chemical Biology, 13 (8). pp. 1996-2002. ISSN 1554-8937
Naveen Kumar, S. K. and Hemshekhar, M. and Sundaram, M. S. and Kemparaju, K. and Girish, K. S. (2017) Cell-free methemoglobin drives platelets to apoptosis via mitochondrial ROS-mediated activation of JNK and p38 MAP kinase. Biochemical and Biophysical Research Communications, 491 (1). 183 - 191. ISSN 0006-291X
Hemshekhar, M. and Thushara, Ram M. and Chandra Nayaka, S. and Sherman, Larry S. and Kemparaju, K. and Girish, K. S. (2016) Emerging roles of hyaluronic acid bioscaffolds in tissue engineering and regenerative medicine. International Journal of Biological Macromolecules, 86. 917 - 928.
Thushara, R. M. and Hemshekhar, M. and Basappa and Kemparaju, K. and Rangappa, K. S. and Girish, K. S. (2015) Biologicals, platelet apoptosis and human diseases: An outlook. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 93 (3). pp. 149-158. ISSN 1879-0461
Sunitha, K. and Hemshekhar, M. and Thushara, R. M. and Santhosh, M. S. and Sundaram, M. S. and Kemparaju, K. and Girish, K. S. (2015) Inflammation and oxidative stress in viper bite: an insight within and beyond. TOXICON, 98. pp. 89-97. ISSN 0041-0101
Paul, M. and Hemshekhar, M. and Thushara, R. M. and Sundaram, M. S. and Naveen Kumar, S. K. and Naveen, S. and Devaraja, S. and Somyajit, K. and West, R. and Basappa and Nayaka, S. C. and Zakai, U. I. and Nagaraju, G. and Rangappa, K. S. and Kemparaju, K. and Girish, K. S. (2015) Methotrexate promotes platelet apoptosis via jnk-mediated mitochondrial damage: alleviation by n-acetylcysteine and n-acetylcysteine amide. PLOS ONE, 10 (6). ISSN 1932-6203
Sharma, R. D. and Katkar, G. D. and Sundaram, M. S. and Paul, M. and Naveen Kumar, S. K. and Swetha Kumar, B. and Hemshekhar, M. and Girish, K. S. and Kemparaju, K. (2015) Oxidative stress-induced methemoglobinemia is the silent killer during snakebite: a novel and strategic neutralization by melatonin. Journal of Pineal Research, 59 (2). pp. 240-254. ISSN 1600-079X
Sundaram, M. S. and Hemshekhar, M. and Santhosh, M. S. and Paul, M. and Sunitha, K. and Thushara, R. M. and Naveen Kumar, S. K. and Naveen, S. and Devaraja, S. and Rangappa, K. S. and Kemparaju, K. and Girish, K. S. (2015) Tamarind seed (tamarindus indica) extract ameliorates adjuvant-induced arthritis via regulating the mediators of cartilage/bone degeneration, inflammation and oxidative stress. SCIENTIFIC REPORTS, 5. ISSN 2045-2322
Naveen Kumar, S. K. and Thushara, R. M. and Sundaram, M. S. and Hemshekhar, M. and Paul, M. and Thirunavukkarasu, C. and Basappa and Nagaraju, G. and Raghavan, S. C. and Girish, K. S. and Kemparaju, K. and Rangappa, K. S. and Chinnaswa (2015) Unconjugated bilirubin exerts pro-apoptotic effect on platelets via p38-mapk activation. Scientific Reports, 5. ISSN 2045-2322
Thushara, R. M. and Hemshekhar, M. and Paul, M. and Shanmuga Sundaram, M. and Shankar, R. L. and Kemparaju, K. and Girish, K. S. (2014) Crocin prevents sesamol-induced oxidative stress and apoptosis in human platelets. Journal of Thrombosis and Thrombolysis, 38 (3). pp. 321-330. ISSN 1573-742X
Katkar, G. D. and Shanmuga Sundaram, M. and Hemshekhar, M. and Sharma, D. R. and Sebastin Santhosh, M. and Sunitha, K. and Rangappa, K. S. and Girish, K. S. and Kemparaju, K. (2014) Melatonin alleviates Echis carinatus venom-induced toxicities by modulating inflammatory mediators and oxidative stress. Journal of Pineal Research, 56 (3). pp. 295-312. ISSN 0742-3098
Srinivasa, V. and Sundaram, M. S. and Anusha, S. and Hemshekhar, M. and Nayaka, S. C. and Kemparaju, K. and Basappa and Girish, K. S. and Rangappa, K. S. (2014) Novel apigenin based small molecule that targets snake venom metalloproteases. PLoS ONE, 9 (9). ISSN 1932-6203
Bharathkumar, H. and Sundaram, M. S. and Jagadish, S. and Paricharak, S. and Hemshekhar, M. and Mason, D. and Kemparaju, K. and Girish, K. S. and Basappa and Bender, A. and Rangappa, K. S. (2014) Novel benzoxazine-based aglycones block glucose uptake in vivo by inhibiting glycosidases. PLoS ONE, 9 (7). ISSN 1932-6203
Jnaneshwari, S. and Hemshekhar, M. and Thushara, R. M. and Sundaram, M. S. and Santhosh, M. S. and Sunitha, K. and Shankar, R. L. and Kemparaju, K. and Girish, K. S. (2014) Sesamol ameliorates cyclophosphamide-induced hepatotoxicity by modulating oxidative stress and inflammatory mediators. Anti-Cancer Agents in Medical Chemistry, 14 (7). pp. 975-983.
Sundaram, M. S. and Hemshekhar, M. and Thushara, R. M. and Santhosh, M. S. and Naveen Kumar, S. K. and Paul, M. and Devaraja, S. and Kemparaju, K. and Rangappa, K. S. and Girish, K. S. (2014) Tamarind seed extract mitigates the liver oxidative stress in arthritic rats. Food Function, 5. pp. 587-597.
Thushara, R. M. and Hemshekhar, M. and Kemparaju, K. and Rangappa, K. S. and Devaraja, S. and Girish, K. S. (2014) Therapeutic drug-induced platelet apoptosis: An overlooked issue in pharmacotoxicology. Archives of Toxicology, 88 (2). pp. 185-198. ISSN 0340-5761
Rakesh, K. S. and Jagadish, S. and Vinayaka, A. C. and Hemshekhar, M. and Paul, M. and Thushara, R. M. and Sundaram, M. S. and Swaroop, T. R. and Mohan, C. D. and Basappa and Sadashiva, M. P. and Kemparaju, K. and Girish, K. S. and Rangappa, K. S. (2014) A new ibuprofen derivative inhibits platelet aggregation and ros mediated platelet apoptosis. PLoS ONE, 9 (9). e2718. ISSN 1932-6203
Santhosh, M. S. and Thushara, R. M. and Hemshekhar, M. and Sunitha, K. and Devaraja, S. and Kemparaju, K. and Girish, K. S. (2013) Alleviation of viper venom induced platelet apoptosis by crocin (Crocus sativus): Implications for thrombocytopenia in viper bites. Journal of Thrombosis and Thrombolysis, 36 (4). pp. 424-432. ISSN 1573-742X
Hemshekhar, M. and Sunitha, K. and Thushara, R. M. and Sebastin Santhosh, M. and Shanmuga Sundaram, M. and Kemparaju, K. and Girish, K. S. (2013) Antiarthritic and antiinflammatory propensity of 4-methylesculetin, a coumarin derivative. Biochimie, 95 (6). pp. 1326-1335.
Hemshekhar, M. and Mohan Thushara, R. and Jnaneshwari, S. and Devaraja, S. and Kemparaju, K. and Girish, K. S. (2013) Attenuation of adjuvant-induced arthritis by dietary sesamol via modulation of inflammatory mediators, extracellular matrix degrading enzymes and antioxidant status. European Journal of Nutrition, 52 (7). pp. 1787-1799. ISSN 1436-6215
Thushara, R. M. and Hemshekhar, M. and Santhosh, M. S. and Jnaneshwari, S. and Nayaka, S. C. and Naveen, S. and Kemparaju, K. and Girish, K. S. (2013) Crocin, a dietary additive protects platelets from oxidative stress-induced apoptosis and inhibits platelet aggregation. Molecular and Cellular Biochemistry, 373 (1-2). pp. 73-83. ISSN 1573-4919
Jnaneshwari, S. and Hemshekhar, M. and Santhosh, M. S. and Sunitha, K. and Thushara, R. and Thirunavukkarasu, C. and Kemparaju, K. and Girish, K. S. (2013) Crocin, a dietary colorant mitigates cyclophosphamide-induced organ toxicity by modulating antioxidant status and inflammatory cytokines. Journal of Pharmacy and Pharmacology, 65 (4). pp. 604-614.
Thushara, R. M. and Hemshekhar, M. and Santhosh, M. S. and Devaraja, S. and Kemparaju, K. and Girish, K. S. (2013) Differential action of phytochemicals on platelet apoptosis: A biological overview. Current Medicinal Chemistry, 20 (8). pp. 1018-1027.
Devaraja, S. and Girish, K. S. and Santhosh, M. S. and Hemshekhar, M. and Nayaka, S. C. and Kemparaju, K. (2013) Fusaric acid, a mycotoxin, and its influence on blood coagulation and platelet function. Blood Coagulation and Fibrinolysis, 24 (4). pp. 419-423.
Sunitha, K. and Suresh, P. and Santhosh, M. S. and Hemshekhar, M. and Thushara, R. M. and Marathe, G. K. and Thirunavukkarasu, C. and Kemparaju, K. and Kumar, M. S. and Girish, K. S. (2013) Inhibition of hyaluronidase by N-acetyl cysteine and glutathione: Role of thiol group in hyaluronan protection. International Journal of Biological Macromolecules, 55. pp. 39-46. ISSN 0141-8130
Girish, K. S. and Paul, M. and Thushara, R. M. and Hemshekhar, M. and Shanmuga Sundaram, M. and Rangappa, K. S. and Kemparaju, K. (2013) Melatonin elevates apoptosis in human platelets via ROS mediated mitochondrial damage. Biochemical and Biophysical Research Communications, 438 (1). pp. 198-204.
Sunitha, K. and Hemshekhar, M. and Thushara, R. M. and Santhosh, M. S. and Yariswamy, M. and Kemparaju, K. and Girish, K. S. (2013) N-Acetylcysteine amide: A derivative to fulfill the promises of N-Acetylcysteine. Free Radical Research, 47 (5). pp. 357-367.
Thushara, R. M. and Hemshekhar, M. and Sunitha, K. and Kumar, M. S. and Naveen, S. and Kemparaju, K. and Girish, K. S. (2013) Sesamol induces apoptosis in human platelets via reactive oxygen species-mediated mitochondrial damage. Biochimie, 95 (11). pp. 2060-2068.
Santhosh, M. S. and Hemshekhar, M. and Sunitha, K. and Thushara, R. M. and Jnaneshwari, S. and Kemparaju, K. and Girish, K. S. (2013) Snake venom induced local toxicities: Plant secondary metabolites as an auxiliary therapy. Mini-Reviews in Medicinal Chemistry, 13 (1). pp. 106-123.
Santhosh, M. S. and Hemshekhar, M. and Thushara, R. M. and Devaraja, S. and Kemparaju, K. and Girish, K. S. (2013) Vipera russelli venom-induced oxidative stress and hematological alterations: Amelioration by crocin a dietary colorant. Cell Biochemistry and Function, 31 (1). pp. 41-50.
Hemshekhar, M. and Sebastin, Santhosh Martin and Kemparaju, K. and Girish, K. S. (2012) Emerging roles of anacardic acid and its derivatives: a pharmacological overview. Basic & Clinical Pharmacology & Toxicology, 110 (2). pp. 122-132. ISSN 1742-7843
Samy, R. P. and Gopalakrishnakone, P. and Stiles, B. G. and Girish, K. S. and Swamy, S. N. and Hemshekhar, M. and Tan, K. S. and Rowan, E. G. and Sethi, G. and Chow, V. T. K. (2012) Snake venom phospholipases A2: a novel tool against bacterial diseases. Current Medicinal Chemistry, 19 (36). ISSN 1875-533X
Hemshekhar, M. and Santhosh, M. Sebastin and Sunitha, K. and Thushara, R. M. and Kemparaju, K. and Rangappa, K. S. and Girish, K. S. (2012) A dietary colorant crocin mitigates arthritis and associated secondary complications by modulating cartilage deteriorating enzymes, inflammatory mediators and antioxidant status. Biochimie, 94 (12). 2723 - 2733. ISSN 1638-6183
Sunitha, K. and Hemshekhar, M. and Santhosh, M. S. and Kumar, M. S. and Kemparaju, K. and Girish, K. S. (2011) Inhibition of hemorrhagic activity of viper venoms by N-acetyl cysteine: Involvement of N-acetyl and thiol groups. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 11 (20). pp. 2589-2600. ISSN 1568-0266
Sunitha, K. and Hemshekhar, M. and Gaonkar, Santosh L. and Santhosh, M. S. and Suresh Kumar, M. and Basappa and Shubha Priya Babu and Kemparaju, K. and Rangappa, K. S. and Nanjunda Swamy, S. and Girish, K. S. (2011) Neutralization of haemorrhagic activity of viper venoms by 1-(3-Dimethylaminopropyl)-1-(4-Fluorophenyl)-3-Oxo-1, 3-dihydroisobenzofuran-5-carbonitrile. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 109 (4). pp. 292-299.
Hemshekhar, M. and Sunitha, K. and Santhosh, M. S. and Devaraja, S. and Kemparaju, K. and Vishwanath, B. S. and Niranjana, S. R. and Girish, K. S. (2011) An overview on genus garcinia: phytochemical and therapeutical aspects. PHYTOCHEMISTRY REVIEWS, 10 (3). pp. 325-351. ISSN 1568-7767
