An overview on genus garcinia: phytochemical and therapeutical aspects

Hemshekhar, M. and Sunitha, K. and Santhosh, M. S. and Devaraja, S. and Kemparaju, K. and Vishwanath, B. S. and Niranjana, S. R. and Girish, K. S. (2011) An overview on genus garcinia: phytochemical and therapeutical aspects. PHYTOCHEMISTRY REVIEWS, 10 (3). pp. 325-351. ISSN 1568-7767

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Official URL: DOI 10.1007/s11101-011-9207-3

Abstract

The genus Garcinia belongs to the family Clusiaceae and has been involved in ayurvedic preparations to medicate various pathophysiological disorders. The bioactive molecules like hydroxycitric acid (HCA), flavonoids, terpenes, polysaccharides, procyanidines and polyisoprenylated benzophenone derivatives like garcinol, xanthochymol and guttiferone isoforms have been isolated from the genus Garcinia. The genus has received the attention of pharmaceutical industries due to their immense remedial qualities. The HCA has been known for its hypolipidemic property. The polyisoprenylated benzophenone and xanthone derivatives are known for their antioxidant, apoptotic, anti-cancer, anti-inflammatory, anti-bacterial, anti-viral, anti-fungal, anti-ulcer, anti-protozoal, and HAT inhibiting properties. Future studies on the synthesis of therapeutically important products and their analogs and evaluation of their safety and efficacy would be of great interest. Though the genus includes more than 300 species, we have made an effort to conceive the curative qualities of bioactive compounds of selected plants to the best of our knowledge.

Item Type: Article
Uncontrolled Keywords: Garcinia; Garcinol; Gambogic acid: caged xanthones; Hydroxy citric acid; Nutritive value; Anti-tumour; Anti-inflammatory; Anti-microbial
Subjects: B Life Science > Biotechnology
Divisions: Department of > Biotechnology
Depositing User: lpa venkatesh user
Date Deposited: 07 Aug 2019 13:11
Last Modified: 07 Aug 2019 13:11
URI: http://eprints.uni-mysore.ac.in/id/eprint/2419

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