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Girish, Y. R. and Anil Kumar, B. M. and Sharath Kumar, K. S. and Hamse, Vivek K. and Prashantha, K. and Sudhanva, M. S. and Shobith, R. (2022) Identification of novel benzimidazole-based small molecule targeting dual targets Tankyrase and Bcl2 to induce apoptosis in Colon cancer. Journal of Molecular Structure, 1269. ISSN 1872-8014
Preetham, H. D. and Umashankara, M. and Sharath Kumar, K. S. and Shobith, R. and Rangappa, K. S. (2022) Identification of beta-aminopyrrolidine containing peptides as beta-amyloid aggregation inhibitors for Alzheimer's disease. Journal of Peptide Science, 28 (6). ISSN 1099-1387
Preetham, H. D. and Umashankara, M. and Sharath Kumar, K. S. and Shobith, R. and Rangappa, K. S. (2022) Pyrrolidine-based cationic gamma-peptide: a DNA-binding molecule works as a potent anti-gene agent. Medicinal Chemistry Research, 31 (3). pp. 507-516. ISSN 1554-8120
Suresha, N. and Metri, Prashant K. and Rashmi, S. and Yang, Ji-Rui and Shobith, R. and Swamynayaka, Ananda and Shanmugam, Muthu K. and Nagaraja, Omantheswara and Madegowda, Mahendra and Babu Shubha, Priya and Chinnathambi, Arunachalam and Alharbi, Sulaiman Ali and Pandey, Vijay and Ahn, Kwang Seok and Lobie, Peter E. and Basappa, B. (2022) Development of 1-(4-(Substituted)piperazin-1-yl)-2-((2-((4-methoxybenzyl)thio)pyrimidin-4-yl)oxy)ethanones That Target Poly (ADP-Ribose) Polymerase in Human Breast Cancer Cells. Molecules, 27 (9). ISSN 1420-3049
Preetham, H. D. and Umashankara, M. and Sharath Kumar, K. S. and Shobith, R. and Rangappa, K. S. (2022) Identification of β-aminopyrrolidine containing peptides as β-amyloid aggregation inhibitors for Alzheimer's disease. Journal of Peptide Science, 28 (6). e3386. ISSN 1099-1387
Preetham, H. D. and Umashankara, M. and Sharath Kumar, K. S. and Shobith, R. and Rangappa, K. S. (2022) Pyrrolidine-based cationic γ-peptide: a DNA-binding molecule works as a potent anti-gene agent. Medicinal Chemistry Research, 31. pp. 507-516. ISSN 1554-8120 (In Press)
Zha, Gao-Feng and Preetham, H. D. and Shobith, R. and Sharath Kumar, K. S. and Girish, Y. R. and Rakesh, K. P. and Ashrafizadeh, Milad and Zarrabi, Ali and Rangappa, K. S. (2021) Benzimidazole analogues as efficient arsenals in war against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies. Bioorganic Chemistry, 115.
Mohan, C. D. and Kim, Chulwon and Siveen, K. S. and Manu, Kanjoormana Aryan and Shobith, R. and Chinnathambi, A. (2021) Crocetin imparts antiproliferative activity via inhibiting stat3 signaling in hepatocellular carcinoma. IUBMB Life, 73 (11). pp. 1348-1362.
Barash, Uri and Shobith, R. and Mohan, C. D. and Vishwanath, D. and Ilanit Boyango and Basappa, B. and Israel Vlodavsky and Rangappa, K. S. (2021) New heparanase-inhibiting triazolo-thiadiazoles attenuate primary tumor growth and metastasis. Cancers, 13 (12). pp. 1-17.
Sajith, Ayyiliath M. and Narasimhamurthy, K. H. and Shanmugam, Muthu K. and Shobith, R. and Nayak, S. Chandra and Chinnathambi, Arunachalam and Alahmadi, Tahani Awad and Alharbi, Sulaiman Ali and Haridas, K. R. and Reddy, E. K. and Savitha, B. and Mohan, C. D. and Rangappa, K. S. (2021) Pyrimidine-2,4-dione targets STAT3 signaling pathway to induce cytotoxicity in hepatocellular carcinoma cells. Bioorganic & Medicinal Chemistry Letters, 50.
Arora, Loukik and Mohan, C. D. and Yang, Min Hee and Shobith, R. and Deivasigamani, Amudha and Kumar, Alan Prem and Kunnumakkara, Ajaikumar B. and Garg, Manoj and Chinnathambi, Arunachalam and Alharbi, Sulaiman Ali and Alahmadi, Tahani Awad and Rangappa, K. S. and Hui, Kam Man and Sethi, Gautam and Ahn, Kwang Seok (2021) Tris(dibenzylideneacetone)dipalladium(0) (Tris DBA) abrogates tumor progression in hepatocellular carcinoma and multiple myeloma preclinical models by regulating the STAT3 signaling pathway. Cancers, 13 (21). pp. 1-23.
Harsha, K. B. and Kavitha, C. V. and Swaroop, T. R. and Shobith, R. and Rangappa, K. S. (2021) A green synthesis of 1,5-benzodiazepines using reusable-heterogeneous silica sulfuric acid catalyst under solvent-free conditions and their antileukemic activity. Asian Journal of Chemistry, 33 (5). pp. 1006-1012.
Dukanya and Shanmugam, M. K. and Shobith, R. and Metri, P. K. and Mohan, S. and Basappa and Rangappa, K. S. (2020) Anti-proliferative activity and characterization data on oxadiazole derivatives. Data in Brief, 31.
Anil, S. M. and Sudhanva, M. S. and Swaroop, T. R. and Vinayaka, A. C. and Rajeev, N. and Kiran, K. R. and Shobith, R. and Sadashiva, M. P. (2020) Base Induced Condensation of Malononitrile with Erlenmeyer Azlactones: An Unexpected Synthesis of Multi-Substituted Delta(2)-Pyrrolines and Their Cytotoxicity. Chemistry & Biodiversity, 17 (5). ISSN 1612-1880
Lee, Jong Hyun and Mohan, C. D. and Deivasigamani, Amudha and Jung, Young Yun and Shobith, R. and Basappa, S. and Chinnathambi, Arunachalam and Alahmadi, Tahani Awad and Alharbi, Sulaiman Ali and Garg, Manoj and Lin, Zhi-Xiu and Rangappa, K. S. and Sethi, Gautam and Hui, Kam Man and Ahn, Kwang Seok (2020) Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma. Journal of Advanced Research, 26. pp. 83-94. ISSN 2090-1224
Dukanya and Shanmugam, Muthu K. and Shobith, R. and Metri, Prashant K. and Mohan, Surender and Basappa and Rangappa, K. S. (2020) Exploring the newer oxadiazoles as real inhibitors of human SIRT2 in hepatocellular cancer cells. Bioorganic & Medicinal Chemistry Letters, 30 (16). ISSN 1464-3405
Somu, C. and Mohan, C. D. and Ambekar, Sachin and Dukanya and Shobith, R. and Baburajeev, C. P. and Sukhorukov, A. and Mishra, S. and Shanmugam, M. K. and Chinnathambi, A. and Awad Alahmadi, T. and Alharbi, S. A. and Basappa and Rangappa, K. S. (2020) Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells. Biotechnology Reports, 25. ISSN 2215-017X
Anil, S. M. and Rajeev, N. and Kiran, K. R. and Swaroop, T. R. and Mallesha, N. and Shobith, R. and Sadashiva, M. P. (2020) Multi-pharmacophore Approach to Bio-therapeutics: Piperazine Bridged Pseudo-peptidic Urea/Thiourea Derivatives as Anti-oxidant Agents. International Journal of Peptide Research and Therapeutics, 26 (1). pp. 151-158. ISSN 1573-3904
Kotian, Sumana Y. and Mohan, C. D. and Merlo, Aloir A. and Shobith, R. and Nayak, S. Chandra and Rai, K. M. Lokanatha and Rangappa, K. S. (2020) Small molecule based five-membered heterocycles: A view of liquid crystalline properties beyond the biological applications. Journal of Molecular Liquids, 297.
Mohan, C. D. and Shobith, R. and Preetham, H. D. and Chandra Nayaka, S. and Gupta, Vijai Kumar and Basappa, S. and Sethi, G. and Rangappa, K. S. (2020) Targeting STAT3 signaling pathway in cancer by agents derived from Mother Nature. Seminars in Cancer Biology.
Lee, Jong Hyun and Mohan, C. D. and Shanmugam, Muthu K. and Shobith, R. and Sethi, Gautam and Siveen, K. S. and Chinnathambi, Arunachalam and Alahmadi, Tahani Awad and Alharbi, Sulaiman Ali and Basappa, S. and Rangappa, K. S. and Ahn, Kwang Seok (2020) Vitexin abrogates invasion and survival of hepatocellular carcinoma cells through targeting STAT3 signaling pathway. Biochimie, 175. pp. 58-68. ISSN 1638-6183
Pandey, Vijay and Wang, Baocheng and Mohan, C. D. and Raquib, Ainiah Rushdiana and Shobith, R. and Srinivasa, V. and Fuchs, Julian E. and Girish, K. S. and Zhu, Tao and Bender, A. and Ma, Lan and Yin, Zhinan and Basappa and Rangappa, K. S. and Lobie, Peter E. (2018) Discovery of a small-molecule inhibitor of specific serine residue BAD phosphorylation. Proceedings of the National Academy of Sciences, 115 (44). E10505-E10514. ISSN 1091-6490
Uzma, Fazilath and Mohan, C. D. and Hashem, Abeer and Konappa, Narasimha M. and Shobith, R. and Kamath, Praveen V. and Singh, Bhim P. and Mudili, Venkataramana and Gupta, Vijai Kumar and Siddaiah, Chandra N. and Chowdappa, Srinivas and Alqarawi, Abdulaziz A. and Abd Allah, Elsayed Fathi (2018) Endophytic Fungi—Alternative Sources of Cytotoxic Compounds: A review. Frontiers in Pharmacology, 9. p. 309. ISSN 1663-9812
Anil, S. M. and Shobith, R. and Kiran, K. R. and Swaroop, T. R. and Mallesha, Ningegowda and Sadashiva, M. P. (2018) Facile synthesis of 1,4-benzodiazepine-2,5-diones and quinazolinones from amino acids as anti-tubercular agents. New Journal of Chemistry, 43 (1). pp. 182-187. ISSN 1369-9261
Mohan, C. D. and Bharathkumar, H. and Dukanya and Shobith, R. and Shanmugam, Muthu K. and Arunachalam, Chinnathambi and Alharbi, Sulaiman Ali and Alahmadi, Tahani Awad and Bhattacharjee, Atanu and Lobie, Peter E. and Deivasigamani, Amudha and Hui, Kam Man and Sethi, Gautam and Basappa and Rangappa, K. S. and Prem Kumar, A. (2018) N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway. Frontiers in Pharmacology, 1125 (9). pp. 1-15. ISSN 1663-9812
Harsha, K. B. and Shobith, R. and Preetham, H. D. and Swaroop, T. R. and Maryam, Gilandoust and Rakesh, K. S. and Rangappa, K. S. (2018) An easy and efficient method for the synthesis of quinoxalines using recyclable and heterogeneous nanomagnetic‐supported acid catalyst under solvent‐free condition. ChemistrySelect, 3 (18). pp. 5228-5232. ISSN 2365-6549
Ananda, H. and Sharath Kumar, K. S. and Sudhanva, M. S. and Shobith, R. and Rangappa, K. S. (2018) A trisubstituted pyrazole derivative reduces DMBA-induced mammary tumor growth in rats by inhibiting estrogen receptor-α expression. Molecular and Cellular Biochemistry, 449 (1-2). pp. 137-144. ISSN 1573-4919
Baburajeev, C. P. and Mohan, C. D. and Shobith, R. and Mason, Daniel J. and Fuchs, Julian E. and Bender, A. and Barash, Uri and Vlodavsky, Israel and Basappa and Rangappa, K. S. (2017) Identification of novel class of Triazolo-Thiadiazoles as potent inhibitors of human Heparanase and their anticancer activity. BMC Cancer, 17 (1). p. 235. ISSN 1471-2407
Anusha, Sebastian and Mohan, C. D. and Ananda, H. and Baburajeev, C. P. and Shobith, R. and Mathai, Jessin and Fuchs, Julian E. and Li, Feng and Shanmugam, Muthu K. and Bender, A. and Sethi, Gautam and Basappa and Rangappa, K. S. (2016) Adamantyl-tethered-biphenylic compounds induce apoptosis in cancer cells by targeting Bcl homologs. Bioorganic & Medicinal Chemistry Letters, 26 (3). 1056 - 1060.
Baburajeev, C. P. and Mohan, C. D. and Patil, Govindagouda S. and Shobith, R. and Pandey, Vijay and Sebastian, Anusha and Fuchs, Julian E. and Bender, A. and Lobie, Peter E. and Basappa and Rangappa, K. S. (2016) Nano-cuprous oxide catalyzed one-pot synthesis of a carbazole-based STAT3 inhibitor: a facile approach via intramolecular C–N bond formation reactions. RSC Advance, 6. pp. 36775-36785.
Anusha, Sebastian and Pandey, Vijay and Mohan, C. D. and Chia, Yi Ting and Shobith, R. and Mathai, Jessin and Baburajeev, C. P. and Paricharak, S. and Mervin, Lewis H. and Bulusu, K. C. and Fuchs, J. E. and Bender, A. and Yamada, Shuhei and Basappa and Lobie, P. E. and Rangappa, K. S. (2016) Novel adamantanyl-based thiadiazolyl pyrazoles targeting EGFR intriple-negative Breast Cancer. ACS Omega, 1 (6). pp. 1412-1424.
Sulaiman, Nurfarhanah Bte Syed and Mohan, C. D. and Basappa, S. and Pandey, V. and Shobith, R. and Bharathkumar, H. and Lobie, P. E. and Prem Kumar, Alan and Rangappa, K. S. (2016) An azaspirane derivative suppresses growth and induces apoptosis of ER-positive and ER-negative breast cancer cells through the modulation of JAK2/STAT3 signaling pathway. International Journal of Oncology, 49 (3). pp. 1221-1229.
Mohan, C. D. and Bharathkumar, H. and Bulusu, K. C. and Pandey, Vijay and Shobith, R. and Fuchs, Julian E. and Shanmugam, M. K. and Dai, Xiaoyun and Li, Feng and Amudha Deivasigamani and Hui, Kam M. and Prem Kumar, A. and Lobie, Peter E. and Bender, Andreas and Basappa, S. and Sethi, G. and Rangappa, K. S. (2014) Development of a novel azaspirane that targets the Janus kinase-signal Transducer and Activator of Transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo. Journal of Biological Chemistry, 289 (49). pp. 34296-34307.
Keerthy, H. K. and Garg, Manoj and Mohan, C. D. and Madan, V. and Kanojia, D. and Shobith, R. and Nanjunda Swamy, S. and Mason, D. J. and Bender, A. and Basappa and Rangappa, K. S. and Koeffler, H. P. (2014) Synthesis and characterization of novel 2-amino-chromene-nitriles that target Bcl-2 in acute myeloid leukemia cell lines. PLoS ONE, 9 (9). ISSN 1932-6203
