Synthesis of podophyllotoxin analogues. xii. synthesis of β-apopicropodophyllin analogues

Nanjundaswamy, N. and Shashikanth, S. and Anjanamurthy, C. and Rai, K. M. Lokanatha (2002) Synthesis of podophyllotoxin analogues. xii. synthesis of β-apopicropodophyllin analogues. Synthetic Communications, 32 (10). pp. 1475-1482. ISSN 1532-2432

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Official URL: https://doi.org/10.1081/SCC-120004135

Abstract

ABSTRACT Tetralone esters (4a–c) on hydroxy methylation with ethyl formate yielded 5a–c which on reduction with sodium borohydride followed by hydrolysis gave dihydroxy acid 8a–c. Base-catalysed cyclisation of 8a–c using p-toluene sulfonyl chloride gave β-apopicropodophyllin analogues (3a–c) in quantitative yield.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Manjula P Library Assistant
Date Deposited: 25 Sep 2019 07:44
Last Modified: 20 Jan 2023 07:49
URI: http://eprints.uni-mysore.ac.in/id/eprint/8514

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