Channe Gowda, D. and Mahesh, B. (2002) New hydrogen donor: A facile Method for the removal of hydrogenolysable protecting groups in peptide synthesis. Protein & Peptide Letters, 9 (3). pp. 225-230. ISSN 1875-5305
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Official URL: http://dx.doi.org/10.2174/0929866023408733
Abstract
Removal of some commonly used protecting groups in peptide synthesis by catalytic transfer hydrogenation employing hydrazinium monoformate and 10%Pd on carbon is described. This method is equally competitive with other methods in deblocking most of the commonly used protecting groups in peptide synthesis. tert-Butyl derived and base labile protecting groups were completely stable under these conditions. This is more effective than hydrazine or formic acid.
| Item Type: | Article |
|---|---|
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Manjula P Library Assistant |
| Date Deposited: | 23 Sep 2019 10:24 |
| Last Modified: | 23 Sep 2019 10:24 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/8387 |
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