Synthesis of new 2-(2,4-dimethoxyphenyl) -1,3,4- oxadiazoles and their antimicrobial activity

Harish, K. P. and Mohana, K. N. (2013) Synthesis of new 2-(2,4-dimethoxyphenyl) -1,3,4- oxadiazoles and their antimicrobial activity. International Journal of Pharma and Bio Sciences, 4 (2). B1046-B1055. ISSN 0975-6299

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Official URL: https://ijpbs.net/abstract.php?article=MjM1MQ==

Abstract

A series of new 2-(2,4-dimethoxyphenyl)-1,3,4-oxadiazole derivatives, 4(a-m) were synthesized by using 2,4-dimethoxybenzoic acid (1) as starting material. Different spectral data were used to characterize the newly synthesized compounds. All the compounds were screened for their in vitro antimicrobial activity. The results indicated that some of the compounds showed potential activity and comparable to those of commercial antibiotics. Few compounds showed good antimicrobial activity against tested strains.

Item Type: Article
Uncontrolled Keywords: article, nonhuman, unclassified drug, drug structure, antibacterial activity, antifungal activity, Bacillus subtilis, bacterial strain, drug synthesis, Escherichia coli, Staphylococcus aureus, 3, antiinfective agent, antimicrobial activity, 4 oxadiazole, 4 oxadiazole derivative, melting point, ethyl 2, Fusarium oxysporum, Xanthomonas campestris, 4 dimethoxyphenyl) 1, 2 (2, 2 (2 bromophenyl) 5 (2, 2 (2 chlorophenyl) 5 (2, 2 (4 bromo 3 fluorophenyl) 5 (2, 2 (4 chlorophenyl) 5 (2, 3 dimethoxyphenyl) 5 (2, 4 bromophenyl) 5 (2, 4 dimethoxybenzohydrazide, 4 dimethoxybenzoic acid, 4 dimethoxyphenyl) 5 (2 fluorophenyl) 1, 4 dimethoxyphenyl) 5 (4 ethoxyphenyl) 1, 4 dimethoxyphenyl) 5 (4 fluorophenyl) 1, 4 dimethoxyphenyl) 5 (4 methoxyphenyl) 1, 4 dimethoxyphenyl) 5 (4 nitrophenyl) 1, 4 dimethoxyphenyl) 5 phenyl 1
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Arshiya Kousar Library Assistant
Date Deposited: 19 Sep 2019 07:01
Last Modified: 19 Sep 2019 07:01
URI: http://eprints.uni-mysore.ac.in/id/eprint/8003

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