Transition metal free intramolecular S-arylation: One-pot synthesis of thiochromen-4-ones

Jenifer Vijay, T. A. and Nandeesh, K. N. and Raghavendra, G. M. and Rangappa, K. S. and Mantelingu, K. (2013) Transition metal free intramolecular S-arylation: One-pot synthesis of thiochromen-4-ones. Tetrahedron Letters, 54 (48). pp. 6533-6537. ISSN 0040-4039

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Abstract

A convenient one-pot method for the synthesis of thiochromen-4-ones by the condensation of 2′-haloacetophenone and dithioesters at room temperature in the presence of NaH in DMF in moderate to good yields has been developed. The method involves unusual intramolecular S-arylation. The reaction is operationally facile, readily scalable and offers rapid entry into substituted chromene-4-ones.

Item Type:	Article
Uncontrolled Keywords:	article, unclassified drug, chemical structure, mass spectrometry, heterocyclic compound, chemical reaction, proton nuclear magnetic resonance, arylation, screening, one pot synthesis, carbon nuclear magnetic resonance, chromene derivative, natural product, thiochromen 4 one, thioflavonone
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	Arshiya Kousar Library Assistant
Date Deposited:	23 Sep 2019 06:21
Last Modified:	23 Sep 2019 06:21
URI:	http://eprints.uni-mysore.ac.in/id/eprint/7945

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