Al-Ghorbani, M. and Lakshmi Ranganatha, V. and Prashanth, T. and Bushra Begum, A. and Naveen, P. and Khanum, S. A. (2013) In vitro antioxidant potential study of triazole and thiadiazole analogues. Journal of Chemical and Pharmaceutical Research, 5 (7). pp. 246-250. ISSN 0975-7384
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Abstract
The synthesis of 3-(2-aroylaryloxy)methyl-5-mercapto-4-phenyl-4H-1, 2, 4-triazole analogues (6a-e) and 2-(2-aroylaryloxy)methyl-5-N-phenylamino-1, 3, 4-thiadiazole (7a-e) were reported earlier. The antioxidant properties of these compounds 6a-e and 7a-e were evaluated by DPPH, nitric oxide and hydrogen peroxide radical scavenging methods. The investigation of antioxidant screening revealed that some of the tested compounds showed good to moderate antioxidant activity. Interestingly, the results show that the compounds containing electron releasing groups like methyl and methoxy exhibit good activities. In the above set of compounds 7e, 6e and 6d have shown very good antioxidant activity.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 1, 1 diphenyl 2 picrylhydrazyl, 2, 2 (2 aroylaryloxy)methyl 5 n phenylamino 1, 3, 3 (2 aroylaryloxy)methyl 5 mercapto 4 phenyl 4h 1, 4 thiadiazole derivative, 4 triazole derivative, Anti-oxidant activities, antioxidant activity, Antioxidant potential, Antioxidant properties, Antioxidants, article, ascorbic acid, controlled study, drug screening, drug structure, drug synthesis, hydrogen peroxide, in vitro study, In-vitro, Methoxy, nitric oxide, Nitric oxide, Organic compounds, Plants (botany), Radical scavenging, thiadiazole derivative, Thiadiazoles, Triazole, triazole derivative, unclassified drug |
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Yuvaraj college > Chemistry |
| Depositing User: | Arshiya Kousar Library Assistant |
| Date Deposited: | 09 Sep 2019 11:03 |
| Last Modified: | 09 Sep 2019 11:03 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/7835 |
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