Comprehensive review on Huisgen's cycloaddition reactions

Ajay Kumar, K. (2013) Comprehensive review on Huisgen's cycloaddition reactions. International Journal of ChemTech Research, 5 (6). pp. 3032-3050.

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Abstract

The 1,3-Dipolar cycloaddition reactions are the classic reaction in modern synthetic organic chemistry. The concept of these reactions was introduced by Huisgen and his co-workers in the early 1960's. 1,3-Dipolar cycloaddition reactions are simple but powerful tool for the construction of five membered heterocycles such as isoxazoles, isoxazolines, pyrazoles, pyrazolones, 1,2,4-oxadiazolines etc. This review comprises of illustrious history, mechanistic path, FMO approach, stereochemistry and synthetic applications of 1,3-dipolar cycloaddition reactions. Recent developments in asymmetric 1,3-dipolar cycloaddition reactions were also discussed.

Item Type:	Article
Uncontrolled Keywords:	1, review, isoxazole derivative, cycloaddition, stereochemistry, pyrazole derivative, dipole, nitrile oxide, pyrazolone, 3 dipolar cycloaddition, calcitriol, colecalciferol, Huisgen reaction
Subjects:	C Chemical Science > Chemistry
Divisions:	Yuvaraj college > Chemistry
Depositing User:	Arshiya Kousar Library Assistant
Date Deposited:	11 Sep 2019 06:09
Last Modified:	18 Jul 2022 10:59
URI:	http://eprints.uni-mysore.ac.in/id/eprint/7826

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