Synthesis of Novel Isoxazolidine Derivatives and Their Antifungal and Antibacterial Properties

Ravi Kumar, K. R. and Mallesha, H. and Rangappa, K. S. (2003) Synthesis of Novel Isoxazolidine Derivatives and Their Antifungal and Antibacterial Properties. Archiv der Pharmazie, 336 (3). pp. 159-164. ISSN 1521-4184

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Official URL: https://doi.org/10.1002/ardp.200390015

Abstract

Abstract The synthesis of some biologically interesting isoxazolidine derivatives has been accomplished by the cycloaddition reaction of C-(4-biphenyl)-N-(3-methylphenyl) nitrone and C-(4-biphenyl)-N-(3-chlorophenyl) nitrone to monosubstituted alkenes. The compounds were screened for their antibacterial and antifungal activities. Among the tested compounds 3a (ii), 3a (vii), 3a (viii), 3b (iv), 3b (vii), and 3b (viii) showed significant antifungal activity comparable with that of the standard drug Nystatin against Botrydiplodia theobromae.

Item Type: Article
Uncontrolled Keywords: Nitrones, Isoxazolidines, Cycloaddition, Antibacterial, Antifungal
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: LA manjunath user
Date Deposited: 09 Sep 2019 06:40
Last Modified: 11 Dec 2019 10:33
URI: http://eprints.uni-mysore.ac.in/id/eprint/7808

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