Synthesis and crystal structure studies of a Novel bioactive Heterocycle: 1-Benzhydryl-4-phenylmethane Sulfonyl Piperazine

Ananda Kumar, C. S. and Naveen, S. and Benaka Prasad, S. B. and Thimmegowda, N. R. and Linge Gowda, N. S. and Sridhar, M. A. and Shashidhara Prasad, J. and Rangappa, K. S. (2007) Synthesis and crystal structure studies of a Novel bioactive Heterocycle: 1-Benzhydryl-4-phenylmethane Sulfonyl Piperazine. Journal of Chemical Crystallography, 37 (11). pp. 727-731. ISSN 1572-8854

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Abstract

1-Benzhydryl-4-phenylmethane sulfonyl piperazine was synthesized from 1-benzhydryl piperazine with phenylmethane sulfonyl chloride. The product obtained was characterized by 1H NMR, MS and IR techniques and finally confirmed by X-ray crystallography. The title compound C24H26N2O2S, Mr = 406.53, crystallizes in the orthorhombic crystal class in the space group Pbca with unit cell parameters a = 11.1240(10)Å, b = 9.4940(15)Å, c = 40.239(4)Å, Z = 8 and V = 4249.7(9)Å3. The structure was solved by direct methods and refined to R1=0.0561 for 2,445 reflections with I > 2 $\sigma$(I). The piperazine ring adopts a chair conformation. The sulfonyl moiety is in a distorted tetrahedral configuration.

Item Type:	Article
Subjects:	C Chemical Science > Chemistry D Physical Science > Physics
Divisions:	Department of > Chemistry Department of > Physics
Depositing User:	C Swapna Library Assistant
Date Deposited:	07 Sep 2019 05:24
Last Modified:	19 Dec 2020 06:02
URI:	http://eprints.uni-mysore.ac.in/id/eprint/7712

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