Manjula, M. K. and Rai, K. M. Lokanatha and Gaonkar, Santosh L. and Raveesha, K. A. and Satish, S. (2009) Synthesis of new series of 5,6-dihydro-4H-1,2-oxazines via hetero diels-alder reaction and evaluation of antimicrobial activity. European Journal Of Medicinal Chemistry, 44 (1). pp. 280-288. ISSN 1768-3254
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A new series of 5,6-dihydro-4H-1,2-oxazines were synthesized via hetero Diels-Alder reaction of alpha-nitrosoolefins with alkenes. alpha-Nitrosoolefins were generated from ketoximes by the action of chloramine-T. The newly synthesized compounds were characterized with IR, NMR, elemental analysis and screened for their antimicrobial activity; they exhibited excellent antimicrobial activity. The minimal inhibitory concentration of the compounds was in the range of 10-35 mu g ml(-1) for bacteria and 10-40 mu g ml(-1) for fungi. (C) 2008 Elsevier Masson SAS. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Synthesis; 1,2-Oxazines; Antimicrobial activity; Chloramine-T |
| Subjects: | B Life Science > Botany B Life Science > Microbiology C Chemical Science > Chemistry |
| Divisions: | Department of > Botany Department of > Chemistry Department of > Microbiology |
| Depositing User: | Users 19 not found. |
| Date Deposited: | 29 Aug 2019 10:06 |
| Last Modified: | 19 Jan 2023 07:17 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/7325 |
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