Zinc (ii) complexes as antimicrobial and DNA cleaving agents: synthesis and spectral characterization

Rakesh, K. P. and Shiva Prasad, K. and Chandan, S. and Shashidhara Prasad, J. (2012) Zinc (ii) complexes as antimicrobial and DNA cleaving agents: synthesis and spectral characterization. International Journal of Pharmaceutical and Chemical Sciences, 1 (3). pp. 930-936. ISSN 2277-5005

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Abstract

The Zinc (II) complexes of 4(3H)-quinazolinone derived Schiff base ligand were prepared. Both free ligand and its Zinc (II) complexes were characterized by elemental analyses, spectral methods (IR, 1HNMR, MS and UV–Vis), molar conductance measurements and thermal studies. The bidentate ligand coordinated to the Zinc (II) ion through the lactum oxygen and the azomethine nitrogen of the ligand. All of the compounds were investigated for their antimicrobial activities against the Gram-positive and Gram-negative bacteria and fungi. The nuclease activity was performed using supercoiled pUC19 plasmid DNA.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Biotechnology
Department of > Chemistry
Depositing User: C Swapna Library Assistant
Date Deposited: 19 Aug 2019 10:43
Last Modified: 11 Jul 2022 07:50
URI: http://eprints.uni-mysore.ac.in/id/eprint/6772

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