T3P®-DMSO mediated one pot cascade protocol for the synthesis of 4-thiazolidinones from alcohols

Sharath Kumar, K. S. and Swaroop, T. R. and Harsha, K. B. and Narasimhamurthy, K. H. and Rangappa, K. S. (2012) T3P®-DMSO mediated one pot cascade protocol for the synthesis of 4-thiazolidinones from alcohols. Tetrahedron Letters, 53 (42). 5619 - 5623. ISSN 0040-4039

Text (Full Text) T3P (R)-DMSO.pdf - Published Version Restricted to Registered users only Download (3MB) | Request a copy

Abstract

Propylphosphonic anhydride (T3P®)-DMSO mediated oxidation of alcohols to carbonyl compounds and their subsequent cyclization with aryl/hetero aryl amines and thioglycolic acid to afford 4-thiazolidinones has been reported. Synthesis of 4-thiazolidinones directly from alcohols has been carried out for the first time. Mild reaction conditions, wide functional group tolerance, ease of work-up, and good yields are the noteworthy features of this protocol.

Item Type:	Article
Uncontrolled Keywords:	Propylphosphonic anhydride (T3P®), Cascade, 4-Thiazolidinones, Thioglycolic acid (or mercaptoacetic acid)
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	C Swapna Library Assistant
Date Deposited:	16 Jul 2019 04:59
Last Modified:	16 Jul 2019 04:59
URI:	http://eprints.uni-mysore.ac.in/id/eprint/5224

Actions (login required)

View Item