D'souza, Stafny M. and Shakunthala, V. (2015) Combined effect of lead acetate and zinc chloride on the fitness of Drosophila Melanogaster. International Journal of Advanced Research, 3 (3). pp. 1054-1064. ISSN 2320-5407
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Abstract
Heavy metals have been considered as one of thekey environmental toxicants with a wide range of health effects on humans. Thebulk of information available today is mainly focused on the single toxinstudies with only few studies enumerating the synergistic, additive orprotective effects of these heavy metals. In current study, Drosophila was usedas a model to investigate the effects of two prominent heavy metals- Lead (Pb)and Zinc (Zn). The developmental time, viability and fertility of these fruitflies after a combined and single exposure to lead acetate and/or zinc chloridewere assessed with a focused aim of learning if the combined exposure at sub-lethal concentrations provokes synergistic changes in the fitness of Drosophilamelanogaster. Larval feeding method was employed throughout the developmentalperiod of the experimental subjects to administer the compounds singly or incombination while maintaining multiple replicates in order to minimizeexperimental error. Subsequently, number of offspring produced, their eclosiontime and viability were recorded. Our results show that developmental exposureof sub lethal concentrations of lead acetate and zinc chloride provokesdisturbances in the fitness of flies. A delay in developmental time was shownwhich is far more pronounced for the combined exposure than single leadintoxication. A synergistic effect was seen on the developmental viability witha survivability of only 10- 28 at combined exposure of zinc and lead. Furtherin contrast to the prior parameters, combined treatment showed a significantincrease in fertility when compared to single exposure of lead acetate-suggesting a protective effect of Zinc over Lead with respect to fertility.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Drosophila melanogaster and Toxicity and Lead Acetate and Zinc Chloride and Fitness |
| Subjects: | B Life Science > Zoology |
| Divisions: | Department of > Zoology |
| Depositing User: | Users 19 not found. |
| Date Deposited: | 08 Jul 2019 10:11 |
| Last Modified: | 05 Aug 2021 06:08 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/4899 |
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