A One-pot tandem approach for the synthesis of 5-(Het)aryloxazoles from substituted (Het)aryl methyl alcohols and benzyl bromides

Vinay Kumar, K. S. and Swaroop, T. R. and Rajeev, N. and Vinayaka, A. C. and Lingaraju, G. S. and Rangappa, K. S. and Sadashiva, M. P. (2016) A One-pot tandem approach for the synthesis of 5-(Het)aryloxazoles from substituted (Het)aryl methyl alcohols and benzyl bromides. Synlett, 27 (9). pp. 1363-1366. ISSN 1437-2096

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Official URL: http://dx.doi.org/10.1055/s-0035-1561391

Abstract

A new modified van Leusen strategy has been developed for the synthesis of biologically significant 5-substituted oxazoles by the reaction of (het)aryl methyl alcohols or benzyl bromides as precursors with tosylmethylisocyanide (TosMIC) under basic conditions. This method is efficient, takes place under mild reaction conditions, and is tolerant of various functional groups with high yield.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Manjula P Library Assistant
Date Deposited: 28 Jun 2019 06:55
Last Modified: 28 Jun 2019 06:55
URI: http://eprints.uni-mysore.ac.in/id/eprint/4043

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