Vinayaka, A. C. and Swaroop, T. R. and Prasanna Kumara, C. and Rangappa, K. S. and Sadashiva, M. P. (2016) Transition-metal-free solid phase synthesis of 1,2-disubstituted 4-quinolones via the regiospecific synthesis of enaminones. RSC Advance, 6 (14). pp. 11528-11535. ISSN 2046-2069
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Herein, the transition-metal-free economical solid phase synthesis of 1,2-disubstituted 4-quinolones has been developed via the novel regiospecific synthesis of enaminones. Notably, a wide range of enaminones were synthesized via a silica-supported solid-phase reaction in good to excellent yields. The transformation of enaminones to 1,2-disubstituted 4-quinolones and N-methyl-2-aryl-4-quinolone alkaloid was achieved in high yield via an alumina-supported solid phase reaction. In addition, all the synthesized compounds were isolated directly in their pure form from the reaction mixture using an easy workup procedure.
| Item Type: | Article |
|---|---|
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Manjula P Library Assistant |
| Date Deposited: | 26 Jun 2019 07:24 |
| Last Modified: | 26 Jun 2019 07:24 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/3878 |
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