Savitha Bhaskaran and Sajith, A. M. and Reddy, Eeda Koti and Ananda Kumar, C. S. and Padusha, M. Syed Ali (2016) Suzuki‐Miyaura cross–coupling reaction in water: facile synthesis of (hetero) aryl uracil bases using pot assium organo trifluoroborates under microwave irradiation. Chemistryselect, 1 (15). pp. 4721-4725. ISSN 2365-6549
Full text not available from this repository. (Request a copy)Abstract
In this paper, we report the use of (hetero) aryl potassiumorganotrifluoroborate salts as versatile nucleophilic organoboron reagents in the Suzuki‐Miyaura cross‐coupling reaction of an electron rich 6‐chloro 3‐methyl uracil in water under microwave irradiation. A comparative study of the cross‐coupling reaction of this chloro uracil analogue with different nucleophilic organoboron source revealed the superior reactivity of (hetero) aryl potassiumorganotrifluoroborates in water under microwave irradiation. Diversely functionalised (hetero) aryl uracil bases, which are known possess a wide range of applications in chemical biology, were efficiently synthesized using this optimised protocol.
| Item Type: | Article |
|---|---|
| Subjects: | D Physical Science > Material Science |
| Divisions: | Department of > Material Science |
| Depositing User: | Manjula P Library Assistant |
| Date Deposited: | 18 Jun 2019 11:40 |
| Last Modified: | 18 Sep 2019 11:38 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/3373 |
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