Rangaswamy, J. and Kumar, H. V. and Harini, S. T. and Naik, N. (2015) An easy access to benzofurans via DBU induced condensation reaction of active 2-hydroxy acetophenones with phenacyl chlorides: a novel class of antioxidant agents. JOURNAL OF HETEROCYCLIC CHEMISTRY, 52 (3). pp. 938-943. ISSN 1943-5193
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A convenient and efficient one-pot synthesis of benzofurans 3a, 3b, 3c, 3d, 3e, 3f, 3g, 3h, 3i, 3j, 3k, 3l, 3m, 3n, 3o, 3p, 3q, 3r, 3s, 3t has been described from 2-hydroxy acetophenones and phenacyl chlorides in the presence of DBU. The procedure was applicable for a variety of phenacyl chlorides and provides a variety of benzofurans with higher yields. DBU acts as a base and as well as nucleophiles. All the derivatives were subjected to in vitro antioxidant screenings against representative 2,2-diphenyl-1-picryl-hydrazyl and 2,2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) radicals and results worth for further investigations.
| Item Type: | Article |
|---|---|
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Users 19 not found. |
| Date Deposited: | 11 Jun 2019 05:56 |
| Last Modified: | 11 Jun 2019 05:56 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/2733 |
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