Spectrophotometric determination of catecholamine using vanadium and eriochrome cyaniner

Nagaraja, P. and Shrestha, A. and Shivakumar, A. and Al-Tayar, N. and Avinas Gowda, K. (2011) Spectrophotometric determination of catecholamine using vanadium and eriochrome cyaniner. QUIMICA NOVA, 34 (3). pp. 373-376. ISSN 0100-4042

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Abstract

A highly sensitive spectrophotometric method for the analysis of catecholamine drugs; L-dopa and methyldopa, is described. The analysis is based on the reaction of drug molecules with vanadium (V) which is reduced to vanadium (IV) and form complex with eriochrome cyanine R to give products having maximum absorbance (lambda(max)) at 565 nm. Beer's law is obeyed in the range 0.028-0.84 and 0.099-0.996 mu g mL(-1) for L-dopa and methyldopa, respectively. The statistical analysis as well as comparison with reported methods demonstrated high precision and accuracy of the proposed method. The method was successfully applied in the analysis of pharmaceutical preparations.

Item Type:	Article
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	Users 23 not found.
Date Deposited:	04 Jun 2019 14:12
Last Modified:	06 Jul 2022 05:48
URI:	http://eprints.uni-mysore.ac.in/id/eprint/2603

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