1,5-diphenylpenta-1,4 dien-3-ones: A novel class of free radical scavengers

Naik, N. and Kumar, H. V. and Swetha, S. (2011) 1,5-diphenylpenta-1,4 dien-3-ones: A novel class of free radical scavengers. BULGARIAN CHEMICAL COMMUNICATIONS, 43 (3). pp. 460-464. ISSN 1359-7345

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Abstract

A series of 1,5-diphenylpenta-1,4-dien-3-ones were synthesized by conjugating benzalacetone with different substituted benzaldehydes. The general synthetic strategy employed for the synthesis of the compounds was based on mixed aldol condensation reaction in the presence of strong base. The structures of newly synthesized compounds were characterized by spectral and elemental analysis. Their radical scavenging activity was evaluated through the determination of their abilities to inhibit free radicals using DPPH(center dot) as a stable radical. Ascorbic acid (AA) was used as reference antioxidant compound and also the comparative study with the synthesized compounds were done. The compounds that showed potential antioxidant activity based on IC(50) value from the highest level were: 2e, 2b and 2a.

Item Type:	Article
Uncontrolled Keywords:	Benzalacetone; aldehydes and radical scavenging activity
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	Users 23 not found.
Date Deposited:	15 Jun 2019 10:10
Last Modified:	15 Jun 2019 10:10
URI:	http://eprints.uni-mysore.ac.in/id/eprint/2592

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