Narasimhamurthy, K. H. and Sajith, Ayyiliath M. and Joy, Muthipeedika N. and Rangappa, K. S. (2020) An Overview of Recent Developments in the Synthesis of Substituted Thiazoles. Chemistryselect, 5 (19). pp. 5629-5656. ISSN 2365-6549
Full text not available from this repository. (Request a copy)Abstract
Thiazole frame work represents a vital pharmacophore in several areas of chemistry. Consequently, several synthetic protocols to construct and functionalize this core, in an attempt to generate diverse thiazole containing architectures have been developed by various researchers across the globe. These wide range of methodologies developed will allow the access to fully decorated thiazole containing new chemical entities that can find various application in the field of medicinal chemistry, agrochemicals and material science. This review will provide an insight in to the various synthons used in construction and diversification of this core. Diversely functionalized thiazole analogs are considered as a vital azole framework present in many natural products. This prominent heterocycle also constitutes an important pharmacophore in medicinal chemistry, in agrochemicals and in molecules for material science applications. All these above-mentioned features of thiazole necessitates the continuous development of efficient methods to access this heterocycle. Accordingly, various researchers across the globe have come up with efficient synthetic protocols in an attempt functionalize different positions of this important scaffold. This review aims at highlighting some of the latest synthetic approaches to di/tri-substituted thiazole analogs which are known to possess a wide spectrum of biological activities.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Heterocycles; Sulfur heterocycles; Synthesis; 1; 3 Thiazoles; Thiazole derivatives |
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Mr Umendra uom |
| Date Deposited: | 18 Feb 2021 07:24 |
| Last Modified: | 07 Jul 2022 07:50 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/15582 |
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