Fuller's earth catalyzed rapid synthesis of bis(indolyl)methanes under solvent free condition

Kapuriya, Naval and Kakadiya, Rajesh and M. S., Mahesh and Pansuriya, Akshay M. and Bhuva, Chirag V. and Anil, S. P. and Piyush, V. P. and Vipul, B. A. and Sarala, G. and Anandalwar, S. M. and Shashidhara Prasad, J. and Anamik , Shah and Yogesh, T. N. (2012) Fuller's earth catalyzed rapid synthesis of bis(indolyl)methanes under solvent free condition. INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 51 (7). pp. 1032-1038.

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Official URL: http://nopr.niscair.res.in/handle/123456789/14361

Abstract

A rapid and highly efficient synthesis of various bis(indolyl)methanes with high yield by the reaction of indoles 1a-c and arylaldehydes 2a'-m' in presence of fuller's earth is demonstrated. This simple and versatile protocol is found to be an efficient catalyst for the electrophilic addition reaction of indole and works well under solvent free condition as well as in aqueous medium. The structure of newly synthesized compound 3m has been confirmed by single crystal X-ray crystallography.

Item Type: Article
Uncontrolled Keywords: Fuller's earth; electrophilic addition; bis(indolyl)-methanes; water mediated; solvent free condition
Subjects: Physical Sciences > Physics
Divisions: PG Campuses > Manasagangotri, Mysore > Physics
Depositing User: Swamy D
Date Deposited: 16 May 2013 11:05
Last Modified: 09 Nov 2015 10:13
URI: http://eprints.uni-mysore.ac.in/id/eprint/9366

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