Comprehensive review on Huisgen's cycloaddition reactions

Ajay Kumar, K. (2013) Comprehensive review on Huisgen's cycloaddition reactions. International Journal of ChemTech Research, 5 (6). pp. 3032-3050.

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The 1,3-Dipolar cycloaddition reactions are the classic reaction in modern synthetic organic chemistry. The concept of these reactions was introduced by Huisgen and his co-workers in the early 1960's. 1,3-Dipolar cycloaddition reactions are simple but powerful tool for the construction of five membered heterocycles such as isoxazoles, isoxazolines, pyrazoles, pyrazolones, 1,2,4-oxadiazolines etc. This review comprises of illustrious history, mechanistic path, FMO approach, stereochemistry and synthetic applications of 1,3-dipolar cycloaddition reactions. Recent developments in asymmetric 1,3-dipolar cycloaddition reactions were also discussed.

Item Type: Article
Uncontrolled Keywords: 1, review, isoxazole derivative, cycloaddition, stereochemistry, pyrazole derivative, dipole, nitrile oxide, pyrazolone, 3 dipolar cycloaddition, calcitriol, colecalciferol, Huisgen reaction
Subjects: C Chemical Science > Chemistry
Divisions: Yuvaraj college > Chemistry
Depositing User: Arshiya Kousar
Date Deposited: 11 Sep 2019 06:09
Last Modified: 11 Sep 2019 06:09

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