Ruthenium (III)-catalyzed oxidative cleavage of phenylpropanolamine with N-bromosuccinimide in hydrochloric acid medium: a kinetic and mechanistic approach

Mohana, K. N. and Ramya, K. R. and Bhandarkar, Ramdas P. M. (2010) Ruthenium (III)-catalyzed oxidative cleavage of phenylpropanolamine with N-bromosuccinimide in hydrochloric acid medium: a kinetic and mechanistic approach. Reaction Kinetics, Mechanisms and Catalysis, 100 (2). pp. 325-335. ISSN 1878-5190

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Abstract

The kinetics of ruthenium (III)-catalyzed oxidative cleavage of phenylpropanolamine (2-amino-1-phenyl-propan-1-ol) (PPA) with N-bromosuccinimide (NBS) in HCl medium has been investigated at 308 K. The oxidation reaction follows the rate law, dNBS/dt = kNBSPPARu(III)aH+−b, where a and b are less than unity. The stoichiometry of the reaction has been found to be 1:1, and benzaldehyde and acetaldehyde were identified as the oxidation products of PPA. The activation parameters have been evaluated from the Arrhenius plot. NBS itself has been postulated as the reactive oxidizing species. The observed results have been explained by plausible mechanisms and the related rate law has been deduced.

Item Type:	Article
Subjects:	B Life Science > Food Science and Nutrition
Divisions:	Department of > Food Science and Nutrition
Depositing User:	LA manjunath user
Date Deposited:	09 Jul 2019 05:48
Last Modified:	21 Jun 2022 07:16
URI:	http://eprints.uni-mysore.ac.in/id/eprint/4966

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