Antioxidative effect and DNA protecting property of moringa oleifera root extracts

Satish, A. and Reddy, P. V. and Sairam, S. and Ahmed, F. and Asna Urooj (2014) Antioxidative effect and DNA protecting property of moringa oleifera root extracts. Journal of Herbs, Spices and Medicinal Plants, 20 (3). pp. 209-220. ISSN 1540-3580

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Moringa oleifera root (dehydrated) powder, extracts - aqueous (WE), acetone (AE) and methanol (ME) were analyzed for phytochemical and antioxidant components by various in vitro assays. The root was found to be a good source of phytochemicals viz, glutathione, a-Tocopherol polyphenols, tannins, alkaloids, saponins. All three solvent extracts exhibited a dose dependent antioxidant activity. The antioxidant properties were established on free radicals; its ability to reduce iron and FeSO4-induced microsomal lipid peroxidation. All three extracts were able to protect DNA from oxidative damage. The suggestive antioxidant mechanism of action of Moringa oleifera is by scavenging reactive oxygen species.

Item Type: Article
Uncontrolled Keywords: concentration response, controlled study, in vitro study, nonhuman, drug screening, adult, animal cell, male, rat, DNA, antioxidant activity, aqueous solution, plant extract, article, alkaloid, saponin derivative, tannin derivative, glutathione, lipid peroxidation, bioassay, oxidative stress, methanol, hydroxyl radical, acetone, plant root, DNA damage, cell protection, IC 50, phytochemistry, polyphenol, root, solvent, tree, Moringa oleifera, Moringa oleifera extract, liver microsome, tocopherol
Subjects: B Life Science > Food Science and Nutrition
Divisions: Department of > Food Science and Nutrition
Depositing User: Arshiya Kousar Library Assistant
Date Deposited: 31 Aug 2019 09:28
Last Modified: 06 Dec 2022 05:16

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