Anticancer effect of silver nanoparticles (AgNP’s) from Decalepis hamiltonii: An in vivo approach

Madhu, C. S. and Balaji, K. S. and Sharada, A. C. and Shankar, J. (2017) Anticancer effect of silver nanoparticles (AgNP’s) from Decalepis hamiltonii: An in vivo approach. Materials Today: Proceedings, 4 (11). 11947 - 11958. ISSN 2214-7853

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In the present study, we are reporting the reduction of silver nitrate by using aqueous root extract of Decalepis hamiltonii to synthesize the silver nanoparticles (AgNP’s). The synthesized silver nanoparticles was characterized by UV-VIS spectrophotometer, Scanning electron microscopy(SEM), Atomic force microscopy(AFM), Dynamic light scattering(DLS), elemental analysis, zeta potential(ZP), Fourier transform infrared spectroscopy (FTIR). The invitro antioxidant activity for AgNP’s was carried out by using DPPH, Hydroxyl radical scavenging activity, and total antioxidant activity against BHA as a standard. Antimicrobial activity of AgNP’s was also carried out against E-coli, B subtilis, S flexineri, P aeruginosa by using disc diffusion method. The anticancer & anti-angiogenic effect of silver nanoparticles was evaluated by using Erlich Ascites murine carcinoma model.

Item Type: Article
Additional Information: INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (ICNANO-2016), APRIL 21-23, 2016, Bangalore, Karnataka
Uncontrolled Keywords: Decalepis hamiltonii, Free radicals, Silver nanoparticles, Antioxidant, Anticancer, Apoptosis
Subjects: C Chemical Science > Biochemistry
Divisions: Department of > Biochemistry
Depositing User: C Swapna Library Assistant
Date Deposited: 18 Jun 2019 09:30
Last Modified: 18 Jun 2019 09:30

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