Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r

Nagaraja, P. and Shrestha, A. and Shivakumar, A. and Al-Tayar, N. and Gowda, A. K. (2011) Spectrophotometric determination of catecholamine using vanadium and eriochrome cyanine r. QUIMICA NOVA, 34 (3). pp. 373-376. ISSN 0100-4042

[img] Text
CHE_2011_Nagaraja, P..pdf

Download (355kB)
Official URL: http://www.scielo.br/pdf/qn/v34n3/02.pdf

Abstract

A highly sensitive spectrophotometric method for the analysis of catecholamine drugs; L-dopa and methyldopa, is described. The analysis is based on the reaction of drug molecules with vanadium (V) which is reduced to vanadium (IV) and form complex with eriochrome cyanine R to give products having maximum absorbance (lambda(max)) at 565 nm. Beer's law is obeyed in the range 0.028-0.84 and 0.099-0.996 mu g mL(-1) for L-dopa and methyldopa, respectively. The statistical analysis as well as comparison with reported methods demonstrated high precision and accuracy of the proposed method. The method was successfully applied in the analysis of pharmaceutical preparations.

Item Type: Article
Uncontrolled Keywords: L-dopa; methyldopa; vanadium
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: lpa venkatesh user
Date Deposited: 04 Jun 2019 14:12
Last Modified: 04 Jun 2019 14:12
URI: http://eprints.uni-mysore.ac.in/id/eprint/2603

Actions (login required)

View Item View Item