Basavaiah, K. and Manjunatha Swamy, J. and Charan, V. S. and Chandrashekar, U. and Prameela, H. C. (2001) Analysis of certain phenothiazine neuroleptics and antihistamines by spectrophotometry using potassium dichromate. East. Pharm., 44. pp. 97-101.
Full text not available from this repository. (Request a copy)Abstract
A simple, rapid and sensitive spectrophotometric method for the determination of trace amounts of phenothiazines in aqueous solution is described. The method was based on the oxidation of the drugs by potassium dichromate in acid solution to form an intense orange or reddish-violet radical cation. A graph of absorbance vs. concentration shows that Beer's law is obeyed over the concentration range 20-250 μgml-1 with molar absorptivity ranging from 0.36 103 to 1.06�103 l.mol-1 cm-1. The method was applied for the anal. of pure drugs and com. formulations containing the studied drugs. The commonly encountered excipients and additives do not interfere with the determination Results of the anal. agree well with those of the official methods.
| Item Type: | Article |
|---|---|
| Additional Information: | Publisher: Eastern Pharmacist |
| Uncontrolled Keywords: | chlorpromazine prochlorperazine maleate determination spectrophotometry, triflupromazine trifluoperazine determination spectrophotometry |
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Dhruva Kumar |
| Date Deposited: | 29 Apr 2021 10:02 |
| Last Modified: | 29 Apr 2021 10:02 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/12715 |
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