Synthesis of novel hesperetin oxime esters: A new discernment in to their antioxidant potential

Nagaraja, N. and Salakatte, T. (2014) Synthesis of novel hesperetin oxime esters: A new discernment in to their antioxidant potential. International Journal of Pharmaceutical Sciences and Research, 5 (4). pp. 1482-1489. ISSN 0975-8232

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Abstract

A series of novel hesperetin oxime esters (3a-l) were synthesized and there in vitro antioxidant potential was examined. Hesperetin oxime 2 was furnished by oximation of hesperetin then subsequently upon esterification with substituted benzoyl chlorides to obtain hesperetin oxime esters (3a-l) in good yields. The structure of compounds was elucidated by elemental analysis, IR, NMR (1H, 13C) and mass spectral studies. Among, the synthesized derivatives compounds (3i-l) showed pronounced antioxidant activity indeed higher than standard butylated hydroxyl anisole (BHA) and ascorbic acid (AA). Compounds with electronegative groups 3a and 3b demonstrated least activity compared to other analogues.

Item Type:	Article
Uncontrolled Keywords:	Hesperetin and Hesperetin Oxime Esters and Radical Scavenging Activity and Antioxidant
Subjects:	C Chemical Science > Chemistry
Divisions:	Department of > Chemistry
Depositing User:	Users 19 not found.
Date Deposited:	11 Nov 2019 11:42
Last Modified:	11 Nov 2019 11:42
URI:	http://eprints.uni-mysore.ac.in/id/eprint/9953

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