Spectrophotometric methods For the determination of Flutamide in Tablets

Nagaraja, P. and Yathirajan, H. S. and Arun Kumar, H. R. and Vasantha, R. A. (2002) Spectrophotometric methods For the determination of Flutamide in Tablets. Indian Journal of Pharmaceutical Sciences, 64 (3). p. 272. ISSN 1998-3743

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Abstract

Simple and sensitive spectrophotometric methods for the determination of flutamide in either pure form or in its pharmaceutical preparations are described. The first method is based on the reaction of reduced flutamide with Ehrlich reagent in alcohol medium to produce a yellow Schiff base with a λmax of 430 nm. In the second method, the diazotisation of reduced flutamide followed by complexation with molybdate ions and pyrocatechol in sulphuric acid medium to give a pink coloured complex with a λmax of 540 nm. Both the methods are highly reproducible and results of the assay of flutamide in tablets compare favourably with the reported method.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: C Swapna Library Assistant
Date Deposited: 02 Nov 2019 09:26
Last Modified: 02 Nov 2019 09:26
URI: http://eprints.uni-mysore.ac.in/id/eprint/9770

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