Tramadol hydro­chloride–benzoic acid (1/1)

Siddaraju, B. P. and Jasinski, Jerry P. and Golen, James A. and Yathirajan, H. S. and Raju, C. R. (2011) Tramadol hydro­chloride–benzoic acid (1/1). Acta Crystallographica Section E, 67 (9). o2351. ISSN 2056-9890

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Official URL: https://doi.org/10.1107/S1600536811032181

Abstract

In the cation of the title co-crystal salt {systematic name: [2-hydroxy-2-(3-meth­oxy­phen­yl)cyclo­hexyl­meth­yl]dimethyl­aza­nium chloride–benzoic acid (1/1)}, C16H31NO2+·Cl−·C7H6O2, the N atom is protonated and the six-membered cyclo­hexane ring adopts a slightly distorted chair conformation. The dihedral angle between the mean planes of the benzene rings in the cation and the benzoic acid mol­ecule is 75.5 (9)°. The crystal packing is stabilized by weak inter­molecular O—H⋯Cl, N—H⋯Cl and C—H⋯π inter­actions, forming a two-dimensional chain network along the b axis. The benzoic acid mol­ecule is not involved in the usual head-to-tail dimer bonding, but instead is linked to the ammonium cation through mutual hydrogen-bonding inter­actions with the chloride anion.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: MUL SWAPNA user
Date Deposited: 24 Oct 2019 06:18
Last Modified: 24 Oct 2019 06:18
URI: http://eprints.uni-mysore.ac.in/id/eprint/9488

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