Govindaraju, M. and Vasanth Kumar, G. and Ajay, K. (2014) Synthesis and antimicrobial activity of novel isoxazolines by 1, 3-dipolar cycloaddition reactions. International Journal of ChemTech Research, 6 (2). pp. 886-890. ISSN 0974-4290
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Abstract
Nitrile oxides were generated by the catalytic dehydrogenation of aromatic aldehyde oximes 2a-g with chloramine-T as oxidizing agent. The 1,3-dipolar cycloaddition of in situ generated nitrile oxides with ethyl oleate 1 produced a series of new ethyl 8-(3-aryl-4-octyl-4,5-dihydroisoxazol-5-yl)octanoate 3a-g in 65- 84 yield. Some of the synthesized cycloadducts have exhibited moderate to good antifungal and antibacterial activity.
Item Type: | Article |
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Uncontrolled Keywords: | Cycloaddition and Dipolar and Isoxazolines and Antifungal and Antibacterial and MIC's. |
Subjects: | C Chemical Science > Chemistry |
Divisions: | Yuvaraj college > Chemistry |
Depositing User: | Users 19 not found. |
Date Deposited: | 18 Oct 2019 09:54 |
Last Modified: | 16 Jul 2022 07:05 |
URI: | http://eprints.uni-mysore.ac.in/id/eprint/9290 |
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