Synthesis, characterization, thermal, anticancer and dna binding properties of co(ii), ni(ii), cu(ii), cd(ii) and zn(ii) complexes with schiff base

Asha, M. S. and Bushra Begum, A. and Rekha and Vasanth Kumar, B. C. and Shaukath Ara, K. (2014) Synthesis, characterization, thermal, anticancer and dna binding properties of co(ii), ni(ii), cu(ii), cd(ii) and zn(ii) complexes with schiff base. International Journal of Medicine and Pharmaceutical Sciences, 4 (3). pp. 41-52. ISSN 2250-0049

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Abstract

A series of metal complexes of Co(II), Ni(II), Cu(II), Cd(II) and Zn(II) were synthesized with newly prepared ligand. This ligand was prepared by the condensation of hydrazide with 2-chloro benzaldehyde. The resulting complexes were characterized by elemental analyses, spectroscopic data i.e. IR, UV, mass, molar electric conductibility as well as magnetic measurements. The complexes were square planar and octahedral in nature. Thermal studies of the complexes were also reported. Metal complexes exhibited DNA binding, cleavage and anticancer activities which were significantly better than the ligand.

Item Type: Article
Uncontrolled Keywords: Schiff Base and Thermal and Angiogenesis and DNA Binding and Metal Complexes
Subjects: C Chemical Science > Chemistry
Divisions: Yuvaraj college > Chemistry
Depositing User: Shrirekha N
Date Deposited: 16 Oct 2019 10:09
Last Modified: 16 Oct 2019 10:09
URI: http://eprints.uni-mysore.ac.in/id/eprint/9214

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