Mitotic spindle irregularities induced by aspirin in Allium cepa.

Shanthamurthy, K. B. and Rangaswamy, V. (1979) Mitotic spindle irregularities induced by aspirin in Allium cepa. Current Science, 48 (23, Co). pp. 1039-41. ISSN 0011-3891

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Exposure of roots of A. cepa to aspirin (I) [50-78-2] at 0.01, 0.02, 0.05, and 0.10% for 3 h at room temp. resulted in lower mitotic indexes compared to the control. Scattering of chromosomes at metaphase and anaphase and irregular formation of cell plates at anatelophase comprised the most dominant types of anomalies. The higher the concn. of I, the greater was the effect. The mitotic inhibiting action of I included the stopping of cell division, an inhibiting action on spindle app., and the prevention of cell wall development at telophase. The spindle anomalies induced by I were due to disturbances of the spindle app. Thus, I is capable of producing a variety of spindle anomalies in A. cepa and is a potential mitotic poison with radiomimetic action. [on SciFinder(R)]

Item Type: Article
Additional Information: Unmapped bibliographic data: PY - 1979/// [EPrints field already has value set] JA - Curr. Sci. [Field not mapped to EPrints]
Uncontrolled Keywords: aspirin mitotic spindle Allium
Subjects: Agriculture Biological Sciences > Botany
University of Mysore > PG Campuses > Manasagangotri, Mysore > Agriculture Biological Sciences > Botany
Divisions: PG Campuses > Manasagangotri, Mysore > Botany
Depositing User: Dhruvakumar
Date Deposited: 17 May 2013 06:01
Last Modified: 17 May 2013 06:25

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