Antibacterial, anthelmintic and antioxidant activity of argyreia elliptica extracts: Activity enhancement by the addition of metal salts

Prashanth, M. K. and Revanasiddappa, H. D. and Rai, K. M. Lokanatha and Raveesha, K. A. and Jayalakshmi, B. (2013) Antibacterial, anthelmintic and antioxidant activity of argyreia elliptica extracts: Activity enhancement by the addition of metal salts. International Journal of Applied Research in Natural Products, 6 (3). pp. 1-10. ISSN 1940-6223

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Argyreia elliptica extracts were prepared with solvents at different polarity (petroleum ether, chloroform, ethyl acetate and methanol) and evaluate their antibacterial, anthelmintic and antioxidant properties first time. An antioxidant activity was analyzed using different in vitro tests namely 2,2-diphenyl-1-picrylhydrazyl (DPPH) and superoxide radical scavenging methods. Quantitative determination of phenols was carried out using spectrophotometric methods. In addition, the extracts were screened for their biological activity in absence and in presence of metal salts Fe(III) and Zn(II) ions. Results indicate that, the tested bacterial strains were most sensitive to the chloroform (CE) and methanol extract (ME). Ethyl acetate (EA), CE and ME extracts showed potent radical scavenging activity. CE and ME extracts showed the highest total phenolic content and its enhanced anthelmintic and antioxidant activities were found in Fe(III) combination. The extracts-Zn(II) ion combination showed enhanced antibacterial activity against tested bacterial strains compare to the extracts alone. Industrial relevance. Herbal medicines have gained increasing attention worldwide for the treatment of various diseases because of their effectiveness and small side effects as compared to synthetic drugs. In general, the essential trace elements have been found to possess a veryimportant role in biological system and also therapeutic activity depends on some trace elements. The present research reports the phytochemical screening of Argyrea elliptica leaves extracts. The antibacterial, anthilmentic and in vitro antioxidant activity activity of extracts and its metal salt combination was studied. The results scientifically establish the efficacy of the plant extracts and its metal salt combination as antibacterial, anthilmentic and antioxidant agents.

Item Type: Article
Uncontrolled Keywords: 1, 1 diphenyl 2 picrylhydrazyl, acetic acid ethyl ester, alkaloid, anthelmintic activity, anthelmintic agent, antibacterial activity, antiinfective agent, antioxidant, antioxidant activity, Argyreia elliptica, Argyreia elliptica extract, article, ascorbic acid, Bacillus subtilis, bacterial strain, butylated hydroxyanisole, carbohydrate, chloramphenicol, chloroform, controlled study, Convolvulaceae, drug potency, drug potentiation, drug screening, Escherichia coli, ferric chloride, flavonoid, IC 50, in vitro study, Metaphire posthuma, methanol, nonhuman, petroleum ether, phenol derivative, phytosterol, piperazine citrate, plant extract, protein, Pseudomonas aeruginosa, quantitative analysis, superoxide, tannin derivative, terpenoid, unclassified drug, zinc sulfate
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Arshiya Kousar Library Assistant
Date Deposited: 23 Oct 2019 05:25
Last Modified: 13 Jan 2023 11:14

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