Nagaraja, P. and Srinivasa Murthy, K. C. and Yathirajan, H. S. (1996) Spectrophotometric determination of isoniazid with sodium 1,2-naphthoquinone-4-sulphonate and cetyltrimethyl ammonium bromide. Talanta, 43 (7). 1075 - 1080. ISSN 1873-3573
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A rapid, sensitive and simple spectrophotometric method is developed for the determination of isoniazid (INH) with sodium 1,2-naphthoquinone-4-sulphonate and cetyltrimethyl ammonium bromide (CTA) in alkaline medium. Beer's law is obeyed in the range of INH concentrations of 2–5.6 μg ml−1 at the maximum absorption of 500 nm. Sensitivity is enhanced by the addition of CTA. The method is successfully employed for the determination of INH in various pharmaceutical preparations and common excipients used as additives in pharmaceuticals do not interfere in the proposed method.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Cetyltrimethyl ammonium bromide, Isoniazid, Pharmaceuticals, Sodium 1,2-naphthoquinone-4-sulphonate, Spectrophotometry |
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | C Swapna Library Assistant |
| Date Deposited: | 14 Oct 2019 05:04 |
| Last Modified: | 18 May 2021 09:25 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/8985 |
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