Synthesis, spectral and antimicrobial studies on Co(ii) complexes of N-Substituted 2-Chloro Phenothiazines

Madhushree, N. N. and Chandrashekara, P. G. and Umesha, S. (2016) Synthesis, spectral and antimicrobial studies on Co(ii) complexes of N-Substituted 2-Chloro Phenothiazines. Indo American Journal of Pharmaceutical Research, 6 (2). pp. 4399-4410. ISSN 2231-6876

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Official URL: https://dx.doi.org/ 10.1044/1980-iajpr.160213

Abstract

The transition metal complexes of Co (II) has been synthesized using 2-chloro phenothiazine derivatives as main ligand and purified by recrystallization in methanol. These have been characterized by elemental analysis, IR, molar conductivity measurement, magnetic studies, TGA, UV and mass. These studies were revealed that an octahedral geometry of the type [M(L)(L1).3H2O] and [M(L)(L1).2H2O], Where M = Co(II), L is ligand, L1 is 1:10-phenathroline. All the metal complexes are mononuclear and have octahedral geometry. Synthesized metal complexes were screened for antimicrobial activities (antifungal and antibacterial) against three bacteria and three fungi using In vitro disc diffusion method. The result revealed that most of the synthesized complex compounds exhibited good antimicrobial activities.

Item Type: Article
Subjects: B Life Science > Biotechnology
Divisions: Department of > Biotechnology
Depositing User: MUL SWAPNA user
Date Deposited: 11 Oct 2019 10:14
Last Modified: 11 Oct 2019 10:14
URI: http://eprints.uni-mysore.ac.in/id/eprint/8906

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