Antibacterial activity of synthetic precursors of Podophyllotoxin

Nanjunda Swamy, N. and Satish, S. and Rai, K. M. Lokanatha and Shashikanth, S. and Raveesha, K. A. (2007) Antibacterial activity of synthetic precursors of Podophyllotoxin. International journal of biomedical science, 3 (2). pp. 113-116. ISSN 1555-2810

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Precursors of podophyllotoxin were synthesized and screened for their antibacterial activity. The results proved that ethyl-2-(3′-methyl-4′-methoxybenzoyl)-3-(4′′ methoxyphenol)-cyclopropane-1-carboxylic acid and Ethyl-2-(3′-methyl-4′-methoxybenzyol-3-1 3″, 4″-dimethoxyphenyl)-cyclopropane-carboxylic acid have significant antibacterial activity against Citrobacter sp., Escherchia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, Shigella sonnei and Streptococcus faecalis. The activity is lower than Ciprofloxacin and equal to Gentamicin and more than Penicillin and Streptomycin.

Item Type: Article
Subjects: B Life Science > Microbiology
C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Department of > Microbiology
Depositing User: C Swapna Library Assistant
Date Deposited: 26 Sep 2019 06:08
Last Modified: 19 Jan 2023 11:29

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