Isolation and characterization of a novel postsynaptic/cytotoxic neurotoxin from Daboia russelli russelli venom

Shelke, R. R. J. and Sathish, S. and Gowda, T. V. (2002) Isolation and characterization of a novel postsynaptic/cytotoxic neurotoxin from Daboia russelli russelli venom. The Journal of Peptide Research, 59 (6). pp. 257-263.

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Official URL: https://doi.org/10.1034/j.1399-3011.2002.02969.x

Abstract

Abstract: A postsynaptic neurotoxin was purified from Daboia russelli russelli venom using gel filtration, ion-exchange chromatography and reverse-phase high-performance liquid chromatography. The N-terminal sequence, molecular mass and pharmacological activities of the neurotoxin/cytotoxin indicate that it is a short-chain neurotoxin like that found in Elapid venom. This is the first report on the presence of such a postsynaptic neurotoxin from D. r. russelli venom.

Item Type: Article
Uncontrolled Keywords: alpha, cytotoxins, Daboia russelli russelli, neurotoxins, Viperidae.
Subjects: C Chemical Science > Biochemistry
Divisions: Department of > Biochemistry
Depositing User: manjula User
Date Deposited: 23 Sep 2019 10:01
Last Modified: 23 Sep 2019 10:01
URI: http://eprints.uni-mysore.ac.in/id/eprint/8383

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