Revanasiddappa, H. D. and Manju, B. G. (2000) Spectrophotometric determination of ritodrine and isoxsuprine hydrochlorides using 4-aminoantipyrine. Journal of AOAC International, 83 (6). pp. 1440-1445. ISSN 1060-3271
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A simple, accurate, and rapid method for the quantitative determination of ritodrine hydrochloride (RTH) and isoxsuprine hydrochloride (ISH) in both pure and dosage forms, is described. The method is based on the development of pink colored product as a result of the condensation of 4-aminoantipyrine with phenols in the presence of an alkaline oxidizing agent, The resulting products are measured at 510 nm for both drugs, with molar absorptivities of 0.98 x 10(4) and 1.20 x 10(4) L/mol cm for RTH and ISH, respectively. A study of the effect of commonly associated excipients revealed that they did not cause interference.
| Item Type: | Article |
|---|---|
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Users 19 not found. |
| Date Deposited: | 19 Sep 2019 09:58 |
| Last Modified: | 19 Sep 2019 09:58 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/8279 |
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