Isolation and characterization of antioxidant and antibacterial compound from mango ginger (Curcuma amada Roxb.) rhizome

Policegoudra, R. S. and Abiraj, K. and Channe Gowda, D. and Aradhya, S. M. (2007) Isolation and characterization of antioxidant and antibacterial compound from mango ginger (Curcuma amada Roxb.) rhizome. Journal of Chromatography B, 852 (1). 40 - 48. ISSN 1570-0232

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Official URL: https://doi.org/10.1016/j.jchromb.2006.12.036

Abstract

The chloroform extract of mango ginger (Curcuma amada Roxb.) rhizome was subjected to antioxidant activity-guided purification by repeated silica gel column chromatography to obtain a pure antioxidant compound. The structure was deduced by analyzing UV, IR, liquid chromatography–mass spectrometry (LC–MS) and two-dimensional heteronuclear multiple quantum coherence transfer spectroscopy (2D-HMQCT) NMR spectral data, and named it as “Amadannulen”, a novel compound. It exhibited DPPH radical scavenging activity, super oxide radical scavenging activity, lipid peroxidation inhibitory activity and metal chelating activity. Amadannulen also showed antibacterial activity against both Gram-positive and Gram-negative bacteria tested. It also exhibited bactericidal activity against M. luteus, B. cereus and B. subtilis.

Item Type: Article
Uncontrolled Keywords: Mango ginger, Rhizome, Antioxidant activity, Antibacterial activity, Amadannulen
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: MUL SWAPNA user
Date Deposited: 16 Sep 2019 09:37
Last Modified: 16 Sep 2019 09:37
URI: http://eprints.uni-mysore.ac.in/id/eprint/8166

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