Reduction of aldehydes and oximes to their corresponding alcohols and amines by catalytic hydrogenation method

Basappa and Doreswamy, B. H. and Mahendra, M. and Mantelingu, K. and Sridhar, M. A. and Shashidhara Prasad, J. and Rangappa, K. S. (2005) Reduction of aldehydes and oximes to their corresponding alcohols and amines by catalytic hydrogenation method. Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry, 44 (1). pp. 148-151. ISSN 0975-0983

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Abstract

The reduction of aldehydes such as 2-butyl-5-chloro-3H-imidazole-5-carbaldehyde and veratraldehyde, which are pharmaceutical key intermediates, have been reduced to alcohols by catalytic hydrogenation method in the presence of magnesium and also oximes are reduced to primary amines successively by magnesium/ammonium formate system, is a large scale feasible and cheaper method. The crystal structure of the product, (2-butyl-5-chloro-3H-imidazole-4-yl)-methanol 1 is reported.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: Manjula P Library Assistant
Date Deposited: 13 Sep 2019 11:03
Last Modified: 22 Nov 2022 09:31
URI: http://eprints.uni-mysore.ac.in/id/eprint/8132

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