Evaluation of new pyrazole derivatives for their biological activity: Structure-activity relationship

Jayaroopa, P. and Vasanth Kumar, G. and Renuka, N. and Harish Nayaka, M. A. and Ajay Kumar, K. (2013) Evaluation of new pyrazole derivatives for their biological activity: Structure-activity relationship. International Journal of PharmTech Research, 5 (2). pp. 819-826. ISSN 0974-4304

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Abstract

A series of new 3-Aryl-4-(4-methoxyphenyl)-1-phenyl-4,5-dihydro-1H-pyrazole-5-carbonitriles (1) were screened in vitro for their antibacterial and antifungal activities against four different organisms. The minimal inhibitory concentration (MIC's) was determined against each organism. The compounds were tested for their antioxidant activity and reducing power ability. The effect of substitution on the activity, and the possible structure activity relationship mechanism of the compounds for their antioxidant activity are presented.

Item Type: Article
Uncontrolled Keywords: article, antioxidant activity, unclassified drug, fungal strain, minimum inhibitory concentration, structure activity relation, antifungal agent, antiinfective agent, streptomycin, biological activity, Gram negative bacterium, Gram positive bacterium, 3 aryl 4 (4 methoxyphenyl) 1 phenyl 4, 5 dihydro 1H pyrazole 5 carbonitrile, griseofulvin, pyrazole
Subjects: C Chemical Science > Chemistry
D Physical Science > Sugar Technology
Divisions: PG Centre Mandya > Sugar Technology
Yuvaraj college > Chemistry
Depositing User: Arshiya Kousar
Date Deposited: 13 Sep 2019 05:41
Last Modified: 13 Sep 2019 05:41
URI: http://eprints.uni-mysore.ac.in/id/eprint/8028

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