Thiadiazoles: Molecules of diverse applications -A review

Ajay Kumar, K. and Vasanth Kumar, G. and Renuka, N. (2013) Thiadiazoles: Molecules of diverse applications -A review. International Journal of PharmTech Research, 5 (1). pp. 239-248.

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Abstract

Thiadiazoles are an important class of heterocyclic compounds that exhibit diverse applications in organic synthesis, pharmaceutical and biological applications. They also known to useful as oxidation inhibitors, cyanine dyes, metal chelating agents, anti-corrosion agents. Attracted by their broad spectrum of applications; researchers across the globe are working on this moiety and consequently have been instrumental in the advancement of thiadiazole chemistry. This review article provides up to date information about developments, exploration of new methods, synthetic strategies, techniques adopted for the synthesis of thiadiazoles and their diverse pharmaceutical activities, structure-activity relationship of the most potent compounds and physical properties. This article can act as an important tool for organic and medicinal chemists to develop newer compounds possessing thiadiazole moiety that could be better agents in terms of efficacy and safety.

Item Type: Article
Uncontrolled Keywords: carbonate dehydratase II, chemoprophylaxis, diabetes mellitus, drug efficacy, drug safety, drug synthesis, gamma interferon, human, Human immunodeficiency virus infection, immunomodulation, inflammation, insecticidal activity, interleukin 10, interleukin 5, Leishmania, matrix metalloproteinase, microsomal aminopeptidase, neoplasm, Niemann Pick disease, nonhuman, pain, physical chemistry, quantitative structure activity relation, review, seizure, thiadiazole derivative, thiosemicarbazide, thiourea
Subjects: C Chemical Science > Chemistry
Divisions: Yuvaraj college > Chemistry
Depositing User: Arshiya Kousar
Date Deposited: 09 Sep 2019 09:44
Last Modified: 09 Sep 2019 09:44
URI: http://eprints.uni-mysore.ac.in/id/eprint/7847

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