Brief review on cyclopropane analogs: Synthesis and their pharmacological applications

Ajay Kumar, K. (2013) Brief review on cyclopropane analogs: Synthesis and their pharmacological applications. International Journal of Pharmacy and Pharmaceutical Sciences, 5 (1). pp. 454-459. ISSN 0975-1491

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The unique reactivity of cyclopropanes due to the high level of strain offers considerable utility in organic synthesis. Many imaginative applications of cyclopropanes as useful building blocks have been predicated on regio-and stereo-controlled ring-opening reactions of substituted cyclopropanes. Cyclopropane analogs have known to exhibit diverse pharmacological applications that created enormous interest in Bioorganic, Medicinal and Pharmaceutical chemistry. This review article depicts the up to date information about the conventional to modified methods of synthesis of cyclopropane analogs and their biological activities. The structure activity relationship was also discussed.

Item Type: Article
Uncontrolled Keywords: allethrin, biological activity, chemical reaction, cyclopropane, cyclopropane derivative, drug synthesis, manganese dioxide, pyrethrin, pyridinium derivative, review, ring closing metathesis, structure activity relation
Subjects: C Chemical Science > Chemistry
Divisions: Yuvaraj college > Chemistry
Depositing User: Arshiya Kousar
Date Deposited: 09 Sep 2019 09:22
Last Modified: 09 Sep 2019 09:22

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