Phthaloyl amlodipine

Yathirajan, H. S. and Nagaraj, B. and Bolte, Michael (2005) Phthaloyl amlodipine. Acta Crystallographica Section E: Crystallographic Communications, 61 (1). o174-o175. ISSN 2056-9890

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Official URL: https://doi.org/10.1107/S1600536804033471

Abstract

The title compound [alternatively called 3-ethyl 5-methyl 4-(2-chloro­phenyl)-2-(2-phthalmidoethoxy­methyl)-6-methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate or ethyl methyl (4RS)-4-(2-chloro­phenyl)-2-({[2-(1,3-dioxo-1,3-di­hydro-2H-isoindol-2-yl)­ethyl]­oxy}methyl)-6-methyl-1,4-di­hydro­pyridine-3,5-di­carboxyl­ate], C28H27ClN2O7, is a calcium channel blocker and belongs to the family of anti-anginal and antihypertensive reagents. The di­hydro­pyridine ring adopts an envelope conformation. The molecular conformation is stabilized by an intramolecular N-H...O hydrogen bond.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: manjula User
Date Deposited: 09 Sep 2019 07:39
Last Modified: 09 Sep 2019 07:40
URI: http://eprints.uni-mysore.ac.in/id/eprint/7820

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