Valdecoxib, a non-steroidal anti-inflammatory drug

Malathy Sony, S. M. and Charles, P. and Ponnuswamy, M. N. and Yathirajan, H. S. (2005) Valdecoxib, a non-steroidal anti-inflammatory drug. Acta Crystallographica Section E: Crystallographic Communications, 61 (1). o108-o110. ISSN 2056-9890

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Official URL: https://doi.org/10.1107/S1600536804032118

Abstract

aldecoxib [systematic name: 4-(5-methyl-3-phenyl­isoxazol-4-yl)benzene­sulfonamide], C16H14N2O3S, a diaryl-substituted isoxazole, is a non-steroidal anti-inflammatory drug (NSAID) that is used for the treatment of rheumatoid arthritis, osteoarthritis and dysmenorrhea pain. The planar isoxazole ring is oriented at angles of 22.2 (1) and 54.3 (1)° with respect to the phenyl and benzene­sulfonamide groups, respectively. N-H...O and C-H...O hydrogen bonds and N-H...[pi], C-H...[pi] and [pi]-[pi] interactions stabilize the crystal packing.

Item Type: Article
Subjects: C Chemical Science > Chemistry
Divisions: Department of > Chemistry
Depositing User: manjula User
Date Deposited: 07 Sep 2019 10:40
Last Modified: 07 Sep 2019 10:40
URI: http://eprints.uni-mysore.ac.in/id/eprint/7786

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