Malathy Sony, S. M. and Charles, P. and Ponnuswamy, M. N. and Yathirajan, H. S. (2005) Valdecoxib, a non-steroidal anti-inflammatory drug. Acta Crystallographica Section E: Crystallographic Communications, 61 (1). o108-o110. ISSN 2056-9890
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Abstract
aldecoxib [systematic name: 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide], C16H14N2O3S, a diaryl-substituted isoxazole, is a non-steroidal anti-inflammatory drug (NSAID) that is used for the treatment of rheumatoid arthritis, osteoarthritis and dysmenorrhea pain. The planar isoxazole ring is oriented at angles of 22.2 (1) and 54.3 (1)° with respect to the phenyl and benzenesulfonamide groups, respectively. N-H...O and C-H...O hydrogen bonds and N-H...[pi], C-H...[pi] and [pi]-[pi] interactions stabilize the crystal packing.
Item Type: | Article |
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Subjects: | C Chemical Science > Chemistry |
Divisions: | Department of > Chemistry |
Depositing User: | Manjula P Library Assistant |
Date Deposited: | 07 Sep 2019 10:40 |
Last Modified: | 07 Sep 2019 10:40 |
URI: | http://eprints.uni-mysore.ac.in/id/eprint/7786 |
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