Yathirajan, H. S. and Nagaraj, B. and Nagaraja, P. and Bolte, Michael (2005) Sildenafil citrate monohydrate. Acta Crystallographica Section E: Crystallographic Communications, 61 (2). o489-o491. ISSN 2056-9890
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Abstract
Sildenafil citrate is well known as Viagra for the treatment of erectile dysfuncion. In the title compound (systematic name: 1-{[3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl}-4-methylpiperazinium citrate monohydrate), C22H31N6O4S+·C6H7O7-·H2O, the pyrazolopyrimidone ring system and the benzene ring are almost coplanar, enabling an intramolecular hydrogen bond between the pyrazolopyrimidone NH group and the O atom of the ethoxy group. One of the N atoms of the piperazine ring is protonated and the citrate molecule exists as an anion. The crystal packing is stabilized by several hydrogen bonds.
| Item Type: | Article |
|---|---|
| Subjects: | C Chemical Science > Chemistry |
| Divisions: | Department of > Chemistry |
| Depositing User: | Manjula P Library Assistant |
| Date Deposited: | 07 Sep 2019 07:38 |
| Last Modified: | 07 Sep 2019 07:38 |
| URI: | http://eprints.uni-mysore.ac.in/id/eprint/7755 |
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